Should I Get the COVID Vaccine While Pregnant or Lactating? - Lynzy & Co.

Should I Get the COVID Vaccine While Pregnant or Lactating?

One of the biggest questions for those that are pregnant or lactating right now is if they should get the COVID vaccine while pregnant or lactating. This can be a very difficult question to answer since the vaccine was not studied in pregnant or lactating women. I wanted to put together this blog post for those of you looking for resources to weigh your decision and have them all in one place. It is important to remember that all of us need to make this decision based on what is right for your family. Every family’s situation is unique and the risks/benefits need to be weighed in order to make your own personal decision. This blog post is written to simply give you the resources you need to help you in your decision making. At the very end I will link out to studies or registries that are currently available if you decide to get the vaccine. These are especially important in collecting data from those of us who are choosing to get the vaccine and put together that much needed research we need. 

UPDATED INFO AS WE GET IT WILL BE ADDED TO THE BOTTOM OF THIS POST!

How do mRNA vaccines work?

mRNA vaccines are NEW but the research behind them is not. Researchers have been studying them for decades and early stage clinical trials have been carried out in the past. You can read more about that here.  The vaccine contains messenger RNA (mRNA) that is encapsulated by a lipid nanoparticle for delivery into host cells. The vaccine utilizes the body’s own cells to create the coronavirus spike protein which then stimulates your immune system to create antibodies against COVID-19. It is important to note that mRNA vaccines are NOT live virus vaccines. These mRNA vaccines will NOT alter your DNA (Advances in mRNA Vaccines & Developing mRNA-vaccine technologies).

Highly suggest this –> Science NEVER sleeps – mRNA vaccines – 60 years in the making

I put together a podcast episode with infectious disease epidemiologist, Jessica Malaty Rivera and we went through 25 of your most asked questions in regards to the COVID vaccine! She is extremely educated on the subject and answers so many of your concerns. 

Via the BMJ, there is no evidence that vaccines can affect fertility

COVID-19 Shot Earlier in Pregnancy Better for Baby || a small study suggests that the earlier a pregnant women receives her vaccine, the more likely she is to transfer those protective antibodies. The study found that “a longer time between vaccination and delivery was associated with greater transfer of COVID-19 antibodies to the baby.”

ACOG | American College of Obstetricians and Gynecologists 

“ACOG recommends that COVID-19 vaccines should not be withheld from pregnant individuals. While safety data on the use of COVID-19 vaccines in pregnancy are limited, there are also no data to indicate that the vaccines should be contraindicated, and no safety signals were generated from DART studies for the Pfizer-BioNtech, Moderna, and Janssen COVID-19 vaccines. “

“ACOG recommends COVID-19 vaccines be offered to lactating individuals. While lactating individuals were not included in most clinical trials, COVID-19 vaccines should not be withheld from lactating individuals who otherwise meet criteria for vaccination. Theoretical concerns regarding the safety of vaccinating lactating individuals do not outweigh the potential benefits of receiving the vaccine. There is no need to avoid initiation or discontinue breastfeeding in patients who receive a COVID-19 vaccine (ABM 2020).”

“As of February 16, 2021, there have been over 30,000 pregnancies reported in CDC’s v-safe post-vaccination health checker (CDC 2021). Based on limited self-reported information, no specific safety signals have been observed in pregnant people enrolled in v-safe; however longitudinal follow-up is needed.”

With regards to fertility:

“Vaccination is strongly encouraged for non-pregnant individuals. Further, ACOG recommends vaccination of individuals who are actively trying to become pregnant or are contemplating pregnancy and meet the criteria for vaccination based on ACIP prioritization recommendations. Additionally, it is not necessary to delay pregnancy after completing both doses of the COVID-19 vaccine.

Importantly, unfounded claims linking COVID-19 vaccines to infertility have been scientifically disproven. ACOG recommends vaccination for all eligible people who may consider future pregnancy. Given the mechanism of action and the safety profile of the mRNA vaccines in non-pregnant individuals, COVID-19 mRNA vaccines are not a cause of infertility. Adenovirus vector vaccines such as the Janssen COVID-19 vaccine cannot replicate following administration, and available data demonstrate that it is cleared from tissues following injection. Because it does not replicate in the cells, the vaccine cannot cause infection or alter the DNA of a vaccine recipient and is also not a cause of infertility (Evans, 2021).”

In a nutshell, making an informed decision based off a risk vs. benefit conversation with your provider is recommended. 

SMFM | Society for Maternal Fetal Medicine

“In general, SMFM strongly recommends that pregnant women have access to COVID-19 vaccines in all phases of future vaccine campaigns, and that she and her healthcare professional engage in shared decision-making regarding her receipt of the vaccine.”

“Healthcare professionals should also counsel their patients that the theoretical risk of fetal harm from mRNA vaccines is very low.”

“However, preliminary developmental and reproductive toxicity (DART) studies for both the Pfizer-BioNtech and Moderna vaccines are encouraging, with no safety signals reported. DART animal studies provide the first safety data to help inform the use of these vaccines in pregnancy until there are more data in this specific population. These studies do not indicate any adverse effects on female reproduction or fetal/embryonal development. ACOG and SMFM strongly urge manufacturers and federal agencies to collect and report data regarding the use of these vaccines in pregnancy”

ACOG & SMFM response to the WHO recommendations for the vaccine in pregnancy | in a nutshell, nothing changes from what they have already recommended above. 

SMFM response to the pause in the J&J vaccine –> here

CDC | Center for Disease Control

“People who are pregnant and part of a group recommended to receive COVID-19 vaccine, such as healthcare personnel, may choose to be vaccinated. A conversation between pregnant patients and their clinicians may help them decide whether to get vaccinated with a vaccine that has been authorized for use under Emergency Use Authorization (EUA).”

“There are no data on the safety of COVID-19 vaccines in lactating women or on the effects of mRNA vaccines on the breastfed infant or on milk production/excretion. mRNA vaccines are not thought to be a risk to the breastfeeding infant. People who are breastfeeding and are part of a group recommended to receive a COVID-19 vaccine, such as healthcare personnel, may choose to be vaccinated.”

ABM | Academy of Breastfeeding Medicine 

“During lactation, it is unlikely that the vaccine lipid would enter the blood stream and reach breast tissue. If it does, it is even less likely that either the intact nanoparticle or mRNA transfer into milk. In the unlikely event that mRNA is present in milk, it would be expected to be digested by the child and would be unlikely to have any biological effects.

“While there is little plausible risk for the child, there is a biologically plausible benefit. Antibodies and T-cells stimulated by the vaccine may passively transfer into milk. Following vaccination against other viruses, IgA antibodies are detectable in milk within 5 to 7 days. Antibodies transferred into milk may therefore protect the infant from infection with SARS-CoV-2.”

ASRM | American Society for Reproductive Medicine

“COVID-19 vaccination is recommended for women who are contemplating pregnancy or who are pregnant in order to minimize risks to themselves and their pregnancy.”

“The Task Force does not recommend withholding the vaccine from patients who are planning to conceive, who are currently pregnant, or who are lactating.”


All of these reputable groups suggest that the decision to receive/not receive the vaccine should be a case by case basis that involves a discussion with one’s provider. 

With regards to infertility/pregnancy, preliminary results in rats show that it is safe thus far. You can read about this on pages 44-45 here

“A combined developmental and perinatal/postnatal reproductive toxicity study of mRNA-1273 in rats was submitted to FDA on December 4, 2020. FDA review of this study concluded that mRNA1273 given prior to mating and during gestation periods at dose of 100 µg did not have any adverse effects on female reproduction, fetal/embryonal development, or postnatal developmental except for skeletal variations which are common and typically resolve postnatally without intervention.”

Other tidbits of information/more resources below:

 “Leaders in Women’s Health Encourage Healthcare Workers to Receive the COVID-19 vaccine” – written by all of the top leaders that I mentioned above! Very informative!

This decision making tool is great for those of you that are pregnant and want to see if the COVID-19 vaccine may be for you.

Moderna mentioned this week that its vaccine does produce neutralizing antibodies (study is not peer reviewed yet) for the UK and South African variants, but it is less effective against the latter. It will be exploring a possible booster shot that would increase efficacy against emerging variants that we are seeing globally.    

This article that talks about a recent study out of Israel is really promising with regards to the Pfizer vaccine and preventing COVID-19 transmission! The study indicates that people who received the vaccine develop and immune response that is significantly stronger than those that experienced COVID and received natural immunity.
 
Many have been worried that the vaccine will not work against the different variants that we are seeing worldwide, here is a link to encouraging news (not peer reviewed yet) that it works against the South African variant! 
 
 
A question I am asked frequently is how often will we need to vaccinate and it looks promising that it may last a few years! We have more research to conduct to figure that out for sure but this is promising! I also loved the explanation here about how the FIRST dose of the vaccine helps you to get that immediate protection (but nothing long term) while the SECOND dose helps to boost that LONG TERM immunity with helper T cells.

 

If you received your COVID vaccine and you are PREGNANT, LACTATING or TRYING TO GET PREGNANT, opt into this registry here! This is a research study that is going to ask you some questions (takes about 20 minutes) and then they will follow-up if / when needed to gather more information! If you are nursing, they will ask you if you would be okay with donating some of your milk to test for antibodies 🙂 

Mother to Baby is currently enrolling in some studies – fill out this form HERE if you are trying to conceive, currently pregnant or breastfeeding and received the vaccine.

Mother’s Milk Study out of UCSD is currently full (this is the one I am in) but will be accepting more participants March 1st. You can also email milk@ucsd.edu to the study coordinators if you have any other questions. They are also accepting donations to help fund the study. You can donate HERE and in the notes section, write “Mommy’s Milk Study”)

Calling all pregnant women <10 weeks! This study is following women all the way through their pregnancy – This UCSF Aspire study is a nationwide prospective cohort study of pregnant women and their offspring during the COVID-19 pandemic. 

If you are PREGNANT and received the MODERNA vaccine: There is a pregnancy exposure registry that monitors pregnancy outcomes in women exposed to Moderna COVID‑19 Vaccine during pregnancy. Women who are vaccinated with Moderna COVID‑19 Vaccine during pregnancy are encouraged to enroll in the registry by calling 1‑866‑MODERNA (1‑866‑663‑3762)

 

My Vaccine Story Update

I am now three weeks POST my second shot! I pumped my last sample of milk for the study last week and will be shipping all the samples out this week! I am so excited! We won’t have results for a little while but I am really optimistic! 

As for symptoms after my vaccine doses…..

I had no side effects after the first dose. 

After the second dose, I had about 36 hours of fever up to 102, body aches and fatigue. It started 12 hours post vaccine. I took Tylenol and Motrin at the 24 hour mark and felt significantly better after that. I would absolutely get the vaccine again despite having some pesky side effects that were completely gone by day 3. I also think I had COVID in the past which is why I may have had a stronger reaction. I know many that have had zero side effects! However, I always want to be 100% transparent and tell you what I experienced personally. 

Link to our story with COVID here

NEW RESEARCH

  • We have our first known case of an infant with SARS-CoV2 IgG antibodies detectable in cord blood after maternal vaccination! This is not peer reviewed yet but I am HERE FOR IT! 🙂 
  • Mom to baby transmission of antibodies | this post written by one of my favorite epidemiologists talks about 3 studies that have proven that mom does transmit antibodies of Sars-CoV-2 to her baby in most cases
  • “There is “absolutely no evidence” that covid-19 vaccines can affect the fertility of women or men, says new expert guidance.” – article in the BMJ found here!
  • Most up to date guidance from SMFM was released on March 3 and states…..”To date, over 30,000 pregnant people have self-reported within the CDC V-safe program, which collects and reports outcomes including miscarriages and stillbirth, pregnancy complications, maternal ICU admissions, adverse birth complications, neonatal death, infant hospitalizations, and birth defects. The reactogencicity and adverse events observed among pregnant people in v-safe DO NOT indicate any concerning pregnancy outcomes, pregnancy complications or neonatal outcomes compared with background data”.      read more here
  • WE HAVE DOCUMENTED ANTIBODIES IN BREASTMILK AFTER VACCINATION!! This moved me to tears this week! Read more about it here! It is a pre print and not peer reviewed but I was VERY confident that we would have antibodies which is now confirmed! 
  • The CDC just released their public health recommendations for those that are fully vaccinate this week!

Tell Me What You Think! leave a comment...

  1. Hi Lynzy,
    Thanks for sharing your Experience. I’m Curious because i’M also Breastfeeding, is your milk A brownish tinge from the vaccine or is that just a filter on the photo? I’Ve seen some moms posting photos of their milk looking more like colostrum During covid and after the Vaccine but Not A brownish tint.

  2. ThaNk you for gEtting the vaccine And being part of the research for fellow lactating mamas! I am currently BF and cant wait until its My turn fOr this shOt. See ya never, covid!
    Have a wondeRful snow day 🙂

    1. Thanks SO mich for sharing! Do you know if they are also doing studies on Any Potential impacts to men whO are trying to conceive? We’re HOping to StArt trying soon

  3. I recently received my second shot anD the Anxiety set in as soon as i walked out Of the room. My biggest concern is fertiliTy. I have been blessed with 2 beautiful children and pray to have more in the future. What is the your opinion on the buZz about fertility and becoming “sterile”. It Honestly sounds stupid coming out of My mouth but as a mother i do worry.

    Would love your thoughts on the tOpic! I have thoroughly ENJOYED following you through this pandemic. You have given me hope Ans put my anxiety at ease! Look forward to following yojr journey in the future!

    Thank you!

  4. FAntastic article. I appreciate all oF the top tier reputable sources for the factual evidenCe. Currently scheduled to get the vaccine just shy of 17 weeks.

  5. Thank You for this amazing summation and gathEring all thIs info! I have put off the vaccine since december sINce i was eligible but not Patient facing. My 9 moNth olds PEDIATRICIAN said go for it as the benefits greatly outweigh the risks so im getting my first dose Saturday and am both excited beyond belief and tErrified at the same time. I trust science and medicine, its just so hard when its your kid that IS going to be Potentially impacted. Your EXPERIENCE Really helped me decide it was worth it To keep me healthy And pOtentially benefit my daughter by giving her antibodies. Thank You so much!

  6. I am so happy you are back! Boy did i miss all your informative poSts. Yhank you so much for all rhe information about the vaccine, which one did Yiu get jf you dont mind me asking. I canT wait to hear The rEsultS of yoUr Study

  7. I think You’re amazing! Nursing mY 2nd little love, 6 months and so hopeful To get the vaccine when AVAILABLE to us in New hampshire! I so APPRECIATE youR insight, research and honesty. My parents will receive theirS in a few weeks, Grateful for scIence. Will breathe a bit easier… Be well Lynzy & thanK you again! -Alli

  8. Hi Lynzy,

    I am in group 1B and had COVID recently. I am hearing conFlicting info about wheTher i can get vaccine ir need to wait 90 days. I was nit treated in any way for COVID. Just 3 advil😉 any research or thoughts. The cdc says its Fine frim what i read.

  9. Lynzy,
    Which vaccine did you get? I got the moderna 3 weeks ago, will be getting my second dOse next week. I have heard the second dose gives you more symptoms of pFizer, but havent heard much about moderna second dose.
    Thank you!

  10. Thank you for sharing the potential research that is avAilable To join. Knowledge is power and i Kept asking my ob how can i join a reSearch study to help other women make informed decision on these vaccines

  11. Hello,
    Thank yOu for sharing. I’m a pregnant Rn and also in clinicAl rotation fOr nP school in nh. I’ve been vaccinated and appreciate seEing stories from others who have too!

  12. I love what you are doing with your platform. I was wondering if there was a specific reason you took tylenol 24 hours after and not earlier since symptoms arose earlier.

  13. Thank you for sharing all of your joUrney and BELIEVING in science. 🥸 Im not in the medical fIeld and have grown kids. 19 & 26! I will look FORWARD to this Blog and your podcasT
    God bless you lynzy ❤️🙏🏻
    LoYal follower

  14. Thank you Lyndzy! I was able to sign up for a stdy. I appreciate you time in compilIng all this information.

  15. Thank you so much for putting all of this information together. I have found these resources to be so helPful and easy to access through Your hard work! So APPRECIATED:-)

  16. Thank you lynzy! Long time follower and I LOVE the new changes your making to your PLATFORM! Healthcare employee here, ttc AND recently RECEIVED my second VACCINE! Feeling great.
    Thank you for being a wealth of knowledge and resource to us mom’s.

  17. Thank you for sharing your research and your expeience with the covid vaccine. I am an NP and was on the fence about getting the vaccine because I was about to have my 3rd baby and concerned about breast feeding. following you on instagram and reading everything you posted really eased my mind and I received the Moderna Vaccine 4 wks post partum. I’m even participating in 2 of the research studies you shared. 🙂

  18. I can’t emphasize how helpful your resources have been to me in arriving at my decision to receive the vaccine while pregnant with our 3rd baby. I regularly refer back to the information you post and share it with other mom’s or soon-to-be mom’s who are just as grateful to have trusted information in one place. I’m 24 weeks pregnant and tomorrow I will receive my first dose. I registered, and have encouraged other pregnant moms, to register for the university of washington study. what a gift it is to give data to future moms in the hope we will make their decision easier than ours was!

  19. Hi!! I am Currently vaccinating patients with one of the large retail pharmacies and Have been sharing the pregnant registry With all of the women who ArE gettinG the vaccine wHile pregnant! TryinG to promote Vaccination in pregnancy where i can 😊

  20. Thank you ThANK YOU! I CHECK BACK OCCASIONALLY TO SEE IF THERE ARE ANY UPDATES AND WONDERED IF YOU, OR ANYONE, HAS COME ACROSS MORE INFO ON JOHNSON & JOHNSON VACCINE AND PREGNANCY?